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Clinical Course And Differential Diagnosis Of Dysentery

Authors

  • Z.O’. Khurramova

    Tashkent State Medical University
    Author
  • G.SH. Boltayeva

    Tashkent State Medical University
    Author

Keywords:

dysentery; shigellosis; differential diagnosis; bloody diarrhea; colitis

Abstract

This review summarizes the clinical features and differential diagnosis of dysentery, primarily shigellosis, based on current literature. Despite declining incidence in some regions, dysentery remains a significant public health concern. The article outlines the disease course from incubation to severe forms, highlighting key symptoms such as bloody diarrhea, abdominal pain, fever, and tenesmus. Special attention is given to vulnerable groups, including children and immunocompromised patients. Diagnostic approaches focus on laboratory confirmation and differentiation from other infectious and non-infectious causes of colitis, including amoebic dysentery, salmonellosis, campylobacteriosis, and Clostridioides difficile infection. Early diagnosis and accurate differentiation are essential for effective management and prevention of complications.

References

Centers for Disease Control and Prevention (CDC). Clinical Overview of Shigellosis – 2024. – URL: https://www.cdc.gov/shigella/hcp/clinical-overview/index.html.

Centers for Disease Control and Prevention (CDC). Shigella – About Infection– 2024. – URL: https://www.cdc.gov/shigella/about/index.html.

DuPont H.L. Bacterial Diarrhea // New England Journal of Medicine. – 2014. – Vol. 370. – P. 1532–1540.

Guerrant R.L., Walker D.H., Weller P.F. Tropical Infectious Diseases: Principles, Pathogens and Practice. – Philadelphia: Elsevier, 2011.

Kotloff K.L., Riddle M.S., Platts-Mills J.A., Pavlinac P., Zaidi A.K.M. Shigellosis // The Lancet. – 2018. – URL: https://www.sciencedirect.com/science/article/abs/pii/S0140673617332968.

Mandell G.L., Bennett J.E., Dolin R. Principles and Practice of Infectious Diseases. – Philadelphia: Elsevier, 2020.

Murray P.R., Rosenthal K.S., Pfaller M.A. Medical Microbiology. – Philadelphia: Elsevier, 2021.

Nataro J.P., Guerrant R.L. Enteric bacterial pathogens // Clinical Infectious Diseases. – 2017.

NCBI StatPearls. Shigellosis [Elektron resurs]. – 2025. – URL: https://www.ncbi.nlm.nih.gov/books/NBK482337/ (murojaat qilingan sana: 22.04.2026).

Riddle M.S., DuPont H.L., Connor B.A. ACG Clinical Guideline: Diagnosis and Management of Infectious Diarrhea // American Journal of Gastroenterology. – 2016.

Ryan K.J., Ray C.G. Sherris Medical Microbiology. – New York: McGraw-Hill, 2018.

Sack D.A., Sack R.B., Nair G.B., Siddique A.K. Cholera // Lancet. – 2004.

Shane A.L., Mody R.K., Crump J.A. et al. 2017 Infectious Diseases Society of America Guidelines for Infectious Diarrhea // Clinical Infectious Diseases. – 2017.

Thielman N.M., Guerrant R.L. Acute infectious diarrhea // New England Journal of Medicine. – 2004.

The Lancet. Shigellosis 2025. – URL: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01033-5/fulltext.

World Health Organization. Shigella. URL: https://www.who.int/teams/immunization-vaccines-and-biologicals/diseases/shigella.

ECDC. Shigellosis – Annual Epidemiological Report– 2022. – URL: https://www.ecdc.europa.eu.

Madiyarov R.S. et al. antimicrobial resistance of Shigella in Uzbekistan // BMC Infectious Diseases. – 2010.

Jawetz E., Melnick J.L., Adelberg E.A. Medical Microbiology. – New York: McGraw-Hill, 2019.

Clinical Microbiology Reviews. Amebiasis and pathogenesis– URL: https://journals.asm.org/doi/10.1128/CMR.00021-19.

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Published

2026-05-07

How to Cite

Z.O’. Khurramova, & G.SH. Boltayeva. (2026). Clinical Course And Differential Diagnosis Of Dysentery. TLEP – International Journal of Multidiscipline, 3(5), 4-9. https://tlepub.org/index.php/1/article/view/991